Diabetes management

In a comprehensive study exploring the interplay between dietary contents and insulin therapy, researchers at the Agricultural University of Athens, along with Harokopio University and the Diabetes Center at Nice General Hospital, have presented eye-opening findings regarding postprandial glucose levels in adults living with type 1 diabetes. A randomized crossover trial scrutinized the effectiveness of the carbohydrate counting method when proteins and fats are also factored into meal composition, specifically looking at the influence of extra virgin olive oil addition. This article delves into the study’s evidence and potential implications for dietary recommendations involving insulin management.

Methodology and Findings

Published in Clinical Nutrition ESPEN under DOI: 10.1016/j.clnesp.2019.03.002, the study involved 20 adults with type 1 diabetes who were put through a series of mixed meals, all measured on the carbohydrate counting methodology. These patients were on intensive insulin therapy, which traditionally relies on carbohydrates only for premeal insulin dosing. The research team, led by Emilia Papakonstantinou and others, challenged this approach by calculating the protein and fat content, with specific attention to the effects of added extra virgin olive oil.

The research had a period of focus that looked at the mean glucose concentration across 6 mixed meals, especially concentrating on 120 minutes postprandially. The meals were designed to be diverse, including pasticcio (a pasta-based dish), grilled chicken with vegetables, and baked giant beans. One of the pivotal outcomes of this study was that the inclusion of olive oil produced a sustained increase in postprandial glucose levels in the pasticcio meal, though the rise remained within the targeted threshold. Notably, such an impact was not significant for the other meals tested.

This revelation suggests that the carbohydrate-counting method remains effective for reaching postprandial glucose targets up to three hours after eating. Interestingly, the addition of minor dietary fat like that found in extra virgin olive oil did not significantly disrupt the postprandial response in low-fat meals. However, it did have a noticeable sustained increase in relation to the high energy density meal, pasticcio.

Implications for Dietary Management in Type 1 Diabetes

These findings can have profound implications for the dietary management strategies employed by individuals with type 1 diabetes. The standard practice of carbohydrate counting is fundamental for many diabetics to maintain glucose control. However, the study’s revelation that the addition of specific types of fat, like extra virgin olive oil, can modulate glucose response, brings a new dimension to dietary planning.

The outcomes of this research insist that a comprehensive understanding of each component within a meal is necessary for accurate insulin dosing. It proves that dietary fat and protein should not be sidelined in the carbohydrate-counting model, particularly if the goal is to maintain glucose levels within target ranges strictly.

Limitations and Future Directions

While this research provides invaluable insights, it also paves the way for more in-depth studies, especially with a larger sample size and diverse populations. Given that the study’s sample was relatively small and culturally specific (all meals were typical to the Greek diet), it would be beneficial for future research to explore a wider variety of cuisines and dietary patterns.

Furthermore, the study was limited to the postprandial period of three hours. Diabetes management often requires long-term monitoring and control. Studying the effects of dietary fats like olive oil over extended periods could provide further guidance to those managing type 1 diabetes and the healthcare professionals who support them.

Keywords

1. Type 1 Diabetes Management
2. Postprandial Glucose Levels
3. Carbohydrate Counting Method
4. Olive Oil and Blood Sugar
5. Insulin Therapy and Diet

References

1. Papakonstantinou, E., Papavasiliou, K., Maouri, C., Magriplis, E., Pappas, S., Bousboulas, S., … Kontogianni, M. D. (2019). Postprandial glucose response after the consumption of three mixed meals based on the carbohydrate counting method in adults with type 1 diabetes. A randomized crossover trial. Clinical Nutrition ESPEN, 31, 48–55. https://doi.org/10.1016/j.clnesp.2019.03.002
2. American Diabetes Association. (2020). Facilitating Behavior Change and Well-being to Improve Health Outcomes: Standards of Medical Care in Diabetes—2020. Diabetes Care, 43(Supplement 1), S48–S65. https://doi.org/10.2337/dc20-S005
3. Smart, C. E., et al. (2013). Both dietary protein and fat increase postprandial glucose excursions in children with type 1 diabetes, and the effect is additive. Diabetes Care, 36(12), 3897–3902. https://doi.org/10.2337/dc13-1231
4. Bell, K. J., et al. (2014). Effect of fat, protein, and glycemic index on postprandial glucose control in type 1 diabetes. Journal of Clinical Endocrinology & Metabolism, 99(12), 4886–4894. https://doi.org/10.1210/jc.2014-2376
5. Paterson, M., Bell, K. J., O’Connell, S. M., Smart, C. E., Shafat, A. and King, B. (2013). The role of dietary fats in the management of type 1 diabetes. Diabetes Spectrum, 26(3), 145–148. https://doi.org/10.2337/diaspect.26.3.145

Ultimately, the study from Papakonstantinou et al. sheds new light on the nuanced dietary needs of those living with type 1 diabetes. It emphasizes the importance of a well-rounded approach to food intake and insulin dosing, one that goes beyond simple carbohydrate counting to incorporate the critical roles of protein and fats in regulating postprandial glucose levels. As dietary management continues to be a cornerstone of diabetes care, adapting to these insights can help patients achieve better glycemic control and improve their quality of life.